New HIV Microbicide Can Be Produced in Transgenic Plants


Scientists have developed a new anti-HIV drug as well as a possible means of producing the drug in large quantities using transgenic plants.

In the research paper, Ma and colleagues describe how they combined two protein microbicides (b12 monoclonal antibody and cyanovirin-N) into a single “fusion” molecule and showed that this molecule is more active against HIV than either of its individual components. They designed synthetic DNA for producing this molecule and introduced this DNA into plant cells. After regenerating transgenic plants that produce the fusion molecule, they prepared the microbicide from a plant extract made by grinding the leaves.


About Author

Leave A Reply