Aggressive Skin Cancer Gene, Found


Cutaneous squamous cell carcinoma (SCC) is an aggressive kind of skin cancer that usually spreads to other parts of the body.

Now, according to a study published by the Arizona Cancer Center, Mayo Clinic and the Translational Genomics Research Institute (TGen), he loss of a gene known as INPP5A could predict the onset and track the progression of cutaneous squamous carcinoma. Targeting the said gene – INPP5A – will provide physicians with better ways of preventing and treating this aggressive skin cancer.

Dr. Jeffrey Trent, President and Research Director of TGen and one of the study’s authors, said:

“At present, our ability to assess who is at risk for SCC and our ability to treat the disease, especially in its aggressive forms, is clearly inadequate. Without question, additional investigations into INPP5A are warranted. Studies like this are critical if we are to ever get a handle on this all-too-common type of skin cancer.”


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