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Diagnostics, Methodologies and Instrumentation
, Stem Cells
by ruth on March 10, 2006
Differentiation is the process by which embryonic stem cells gradually turn into function specific type of adult cells or so-called "cell lineages", including skin, heart or brain cells.
The main challenge facing stem cell research is that of guiding differentiation along these well-defined controlled lineages. Stem cells grown in the laboratory tend to differentiate in an uncontrolled manner, resulting in a mixture of cells of little medical use.
The team of researchers at the University of Wisconsin-Madison have shown that by mechanically straining the cells as they grow, the uncontrolled differentiation in stem cells is significantly reduced, if not eliminated. The team reported this liquid crystal-based cell culture system in an article in the March issue of Advanced Functional Materials.
[Source: UW-Madison]
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