biotech
Two Protein Receptors Control Stomach Relaxation Identified
Filed in archive Genomics, Proteomics and Bioinformatics by ruth on March 5, 2008
Two Protein Receptors Control Stomach Relaxation Identified
Scientists have identified 2 protein receptors in a guinea pig - P2Y1 and P2Y11 - that relax the gut and thus allow it to accommodate a bigger meal. these receptors are also present in humans and may serve as targets for developing drugs to aid in weight management and preventing obesity.

Dr Brian King of the UCL Department of Neuroscience, Physiology and Pharmacology says: "The mechanisms we have identified are important to the normal workings of the stomach - a hollow organ which actively relaxes to help accommodate the size of your meal. The human stomach has a 'resting' internal volume of 75 millilitres but, by relaxing its muscular wall, can expand to an internal volume of two litres or more - a 25-fold increase in the volume it can accept. This expansion is controlled by nerves inside the stomach wall and these nerves release molecules that stimulate the P2Y1 and P2Y11 receptor proteins embedded in muscle cells in the gut wall.


Blocking these receptors may prevent the relaxation of the stomach, and may thus help in regulating an individual's food intake, possibly in a similar mechanism as a lapband surgery would.

Source

Related Entries:

Permalink: Two Protein Receptors Control Stomach Relaxation Identified
Tags: proteomics  lapband  lapband+surgery  weight+control  obesity  weight+gain  weight+loss  weight+management 
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/118028
img Addthis img Ask img Blinklist img del.icio.us img Digg img Fark img Facebook img Google img Lycos img Ma.gnolia Add this page to Mister Wong Mr Wong img Netscape img Netvousz img Newsvine img Reddit img StumbleUpon img Slashdot img Tailrank img Technorati img Wink img Yahoo

Vote for Two Protein Receptors Control Stomach Relaxation Identified:

  • Currently 7.50/10
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • 10
Rating: 7.50 out of 4 vote(s) cast.
Subscribe
Share It
Popular posts from our other blogs:
RSSrss
See all blog subscribe options
Google google
What is RSS?
Yahoo! yahoo
Addthis Subscribe using any feed reader!
Bloglines Bloglines
Newsletter

TwitterFollow us on Twitter!