Sleep Regulator Melatonin Lowers Blood Pressure

Filed in archive Drugs, Vaccines and Therapeutics on February 3, 2006

This entry is submitted by Gloria Gamat, via Creative Reporter.The naturally occurring hormone, Melatonin, which can be taken orally to regulate sleep patterns, lowers blood pressure in women as claimed by Italian researchers in the new study, published in the American Journal of Hypertension (Vol. 18, pp. 1614-1618):

Although the study was limited to 18 middle-aged women, half of whom had hypertension, the results strongly indicate that prolonged intake of melatonin could improve the day-night BP rhythm.

"A 10 per cent decline of BP over daytime values is considered appropriate to reduce the cardiovascular risk," said lead-author Angelo Cagnacci. "During placebo use only 39 per cent of the subjects reached this value, but this rate surged to 84 per cent during melatonin administration."

The mechanism whereby melatonin reduces BP is still unknown, but the researchers propose it is not merely due to the sleep-inducing effect of the hormone. In this study, the interactions with other antihypertensive therapies were excluded but should certainly be investigated.

"Longer clinical trials are necessary for a full exploration of the potential effects of melatonin," concluded Cagnacci.

About Gloria Gamat: Gloria is a proud single-mom to Raine (Rainier Brando: born 29 December 2002) and a Chemist. Gloria also blogs about motherhood at EMothersOnline and about life and travel in the Philippines at The Philippine Culture Blog and at Pinoy Travel Blog respectively.

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Tags: hypertension melatonin biotech sleep pressure blood+pressure lowers+blood sleep+regulator

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Response from: mitch (05/17/07 8:20pm)

Hi Thanks for a great article on melatonin Gloria. Isn't melatonin already a proven stress reducer?

I am just looking around the web doing a little research on hypertension and high blood pressure.

I want to find out more about treating high blood pressure symptoms with natural treatments.http://www.high-blood-pressure-symptoms.info/

Do you have any idea how much prescription hypertension meds cost?

Response from: paradise philippines (09/21/07 3:27am)

Thanks for a very informative article... Just one question, is melatonin effective when taken off-hours?

Response from: Shannon (11/01/07 3:08am)

Hi,
Great article. I started taking melatonin a few weeks ago to help me sleep. I didn't know about the blood pressure lowering properties until I googled it after noticing that mine had dropped 40 points in two weeks even though I haven't been taking my b/p meds. (too expensive). I hope there are more studies done on this as I would like to know about possible side effects. So far though it's been really good for me. I'm sleeping much better and the lower blood pressure is a huge bonus!

Response from: Straightfromthedoc

The British Medical Journal published a study showing no evidence that melatonin is effective in treating secondary sleep disorders or preventing jet lag. Sleep disorders are a widespread problem and place a burden on society through their negative imp...

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