biotech
Rhodococcus Antibiotic Effective Against H.pylori
Filed in archive Drugs, Vaccines and Therapeutics , Microbiology by ruth on February 27, 2008
Rhodococcus Antibiotic Effective Against H.pylori
By growing them together with a strain of Steptomyces, scientists were able to trigger anitbiotic production in Rhodococcus, a soil bacteria that does not normally produce antibiotics but whose genome has been noted to code for several secondary metabolites.

The researchers isolated the antibiotic, dubbed it rhodostreptomycin and started testing it to see what else it would kill. It proved effective against many other strains of bacteria, most notably Helicobacter pylori. Rhodostreptomycin is a promising candidate to treat H. pylori because it can survive in very acidic environments such as the stomach.

The antibiotic turned out to be a type of molecule called an aminoglycoside, composed of peculiar sugars, one of which has a ring structure that has not been seen before. The ring structure could offer chemists a new target for modification, allowing


More details from the MIT News.


Permalink: Rhodococcus Antibiotic Effective Against H.pylori
Tags: anitbiotics  microbiology  h+pylori  pylori  pyloric+ulcer  2007  effective+against  rhodococcus+antibiotic 
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