Protein Biomarkers Predict Bladder Cancer Recurrence and Survival
Filed in archive Diagnostics, Methodologies and Instrumentation , Genomics, Proteomics and Bioinformatics by ruth on February 06, 2007

The proteins Bcl-2, caspase-3, P53 and survivin --proteins known to regulate apoptosis -- were associated with the rate of mortality from cancer after surgery.
Patients who showed no mutations in the four biomarkers had a 90 percent chance of survival at five years compared to less than 20 percent if they had four mutated markers.
Although the authors say that the data are still preliminary and would need to be scientifically validated, the findings suggest that mutations on all four markers could indicate the need for adjuvant chemotherapy to increase survival rates among such patients.
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cancer proteomics diagnostics biomarkers genomics biotech bladder+cancer protein+biomarkers
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