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Drugs, Vaccines and Therapeutics
, Food and Agriculture
by ruth on May 21, 2008
© Harris Graber
Graduate research assistant Saebyeol jang studied the inflammatory response in microglial cells. She spurred inflammation by exposing the cells to lipopolysaccharide (LPS), a component of the cell wall of many common bacteria.
Those cells that were also exposed to luteolin showed a significantly diminished inflammatory response. Jang showed that luteolin was shutting down production of a key cytokine in the inflammatory pathway, interleukin-6 (IL-6). The effects of luteolin exposure were dramatic, resulting in as much as a 90 percent drop in IL-6 production in the LPS-treated cells.
In vivo experiments in mice also showed similar results. The authors suggest that these results indicate a possible role for luteolin in treating neuroinflammation.
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Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/124169
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Vote for Plant Flavonoid Luteolin Reduce Inflammatory Response in the Brain:
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Response from:
Ann
(05/22/08 10:57am)
Green peppers, mean bell peppers or hot green peppers???
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