Novel Anti-freeze Proteins From Snow Fleas

Filed in archive Genomics, Proteomics and Bioinformatics on October 25, 2005

Researchers from Queen's University may have discovered a means to prolong the preservation period for organs for transplantation. Using a process called ice affinity purification, the researchers were able to isolate a novel antifreeze glycine-rich protein from snow fleas. The results of their study, are published in this week's issue of Science.

Researchers also claim that this novel anti-freeze protein (AFP) is better than previously discovered anti-freeze proteins found in moths and beetles:

"Unlike the antifreeze proteins in beetles and moths, AFPs in snow fleas break down and lose their structure at higher temperatures," explains Dr Davies, Canada Research Chair in Protein Engineering. "This means that if used to store organs for transplants, they will be cleared from a person's system very quickly, reducing the possibility of harmful antibodies forming."

Researchers also see other potential use of this novel protein:

As well as its potential for use in organ transplants, the researchers suggest it could help to increase frost resistance in plants, and inhibit crystallization in frozen foods.

Read more from Queen University's press release.