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Corporate and Industrial News
, Drugs, Vaccines and Therapeutics
by ruth on April 26, 2007
Phase II trials have indicated that this potentially first-in-class vaccine, called CYT002-NicQb ("NicQb"), has the potential to promote abstinence from smoking in patients who achieved high antibody levels following vaccination. A subsequent study determined the optimal dose for future trials, and this compound is set to enter Phase III trials in late 2008.
NicQb acts by inducing the body to develop antibodies - a class of blood proteins generated by the immune system - that bind specifically to nicotine molecules in the bloodstream. The resulting complex is too large to cross the blood-brain barrier, significantly reducing the uptake of this highly addictive substance and preventing the so-called "nicotine high," a form of stimulation that can cause a significant failure rate in people attempting to quit smoking.
More from Novartis' press release or the International Herald Tribune report. More about NicQb from SmokersVaccine.com.
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