New HIV Microbicide Can Be Produced in Transgenic Plants
Filed in archive Drugs, Vaccines and Therapeutics , Genomics, Proteomics and Bioinformatics on May 29, 2009
© Sully PixelScientists have developed a new anti-HIV drug as well as a possible means of producing the drug in large quantities using transgenic plants.
In the research paper, Ma and colleagues describe how they combined two protein microbicides (b12 monoclonal antibody and cyanovirin-N) into a single "fusion" molecule and showed that this molecule is more active against HIV than either of its individual components. They designed synthetic DNA for producing this molecule and introduced this DNA into plant cells. After regenerating transgenic plants that produce the fusion molecule, they prepared the microbicide from a plant extract made by grinding the leaves.
The study has been published in the latest issue of FASEB.
Source
© Sully Pixel
Tags: hiv microbicide aids transgenics genetics more transgenic+plants produced+transgenic
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