Nestin: A Biomarker for Basal Epithelial Breast Cancer

Filed in archive Diagnostics, Methodologies and Instrumentation , Genomics, Proteomics and Bioinformatics by ruth on January 16, 2007

Last month, we reported on two proteins considered to be biomarkers for breast cancer metastasis onto neighboring lymph nodes. This time, a structural protein called nestinhas been linked to the incidence of basal epithelial breast tumors, a particularly deadly form of breast cancer. Since this type of breast cancer has a high rate of recurrence, testing for the nestin biomarker could lead to earlier detection and better treatment.

"Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansion of the basal epithelia." DiRenzo said. "If it is indeed specific to regenerative cells, then it will make for an excellent diagnostic tool for a cancer of regenerative mammary cells."

Read more from the American Association for Cancer Research, or see the January 15 issue of the Cancer Research journal.

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Biomarker Test for Bladder Cancer Recurrence and Survival - 20 February 2007
You Don't Have to Be a Woman to Support Breast Cancer Rease... - 06 September 2007
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Urban Women Face Higher Risk for Breast Cancer - 26 November 2007

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Permalink: Nestin: A Biomarker for Basal Epithelial Breast Cancer

Tags: cancer diagnostics biomarker breast+cancer breast basal+epithelial nestin+biomarker

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Vote for Nestin: A Biomarker for Basal Epithelial Breast Cancer:

Currently 8.67/10
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Rating: 8.67 out of 3 vote(s) cast.

Response from: Daniel Tzu-bi Shih (11/25/07 10:29pm)

I agree the nestin is one of the essential biomarkers for epithelial derived cancers

Response from: Dr.Mona (12/23/07 10:35am)

if u pleasr inform me any recent papers abou nestin as a marker in breast cancer

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