Multipotential Stem Cells from Menstrual Blood

Filed in archive Stem Cells on April 25, 2008

In the new issue of Cell Transplantation a study demonstrated the potentials of menstrual blood as a source of stromal stem cells with the ability to differentiate into a variety of cell lineages.

Tests showed that MenSCs could differentiate into adipogenic, chondrogenic, osteogenic, ectodermal, mesodermal, cardiogenic, and neural cell lineages. According to Patel, the sample MenSCs expanded rapidly and maintained greater than 50 percent of their telomerase activity when compared to human embryonic stem cells and better than bone marrow-derived stem cells. "Studies have demonstrated that MenSCs are easily expandable to clinical relevance and express multipotent markers at both the molecular and cellular level," concluded Patel.

Researchers emphasized the importance of the abundance and plasticity of MenSCs. Based on the results of their studies, they noted the potential for MenSCs in regenerative transplantation therapies for many different organs and tissues. "The need for regenerative therapies using cells with the ability to engraft and differentiate is vast," said Patel.

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