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Drugs, Vaccines and Therapeutics
, Microbiology
by ruth on April 24, 2007
Dr. Bible's team has shown for the first time that chaetocin has promising anti-myeloma activity. They found that chaetocin's promise includes the ability to:
* Kill myeloma cells harboring a diverse array of genetic abnormalities
* Cause biological changes and induce oxidative stress in myeloma cells, leading to their death
* Selectively kill myeloma cells with superior efficacy to commonly-used anti-myeloma drugs including dexamethasone and doxorubicin
* Reduce myeloma growth in mice
* Rapidly accumulate in cancer cells
The authors say that it will still take a few years before human clinical trials can be made, though. The study is published in the latest issue of Blood.
Permalink: Mold By-Product Chaetocin May Treat Myeloma
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What: "Leukemia, Lymphoma, Myeloma and Bone Marrow Transplantation" Free Educational Symposium
When: June 11, 2008 4-8 pm
Where: Moffitt's Stabile Research Building, 12902 Magnolia Drive Tampa, Florida
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