Molar Pregnancy Traced to NALP7 Gene Mutations
Filed in archive Diagnostics, Methodologies and Instrumentation , Genomics, Proteomics and Bioinformatics on February 8, 2006
A molar pregnancy is a kind of aberration that occurs during fertilization, wherein although the symptoms of pregnancy manifest themselves, there is no embryo formed. Moreover, there is an possibility of the "mole" (placental parts without fetus) developing into cancer.
Researchers from the McGill University Health Center may have traced the genetic cause underlying this condition to gene located on chromosome 19. Their findings will be published in next month's issue of Nature Genetics.
"We believe that the NALP7 gene, which is involved in inflammation, plays a role not only in repeated molar pregnancies but also in other forms of reproductive failure such as spontaneous abortions and stillbirths," says MUHC geneticist Rima Slim. "Our findings will open new avenues of research to better understand the genetic basis of various forms of reproductive failure."
These finding could provide the basis for the development of future screening and diagnosis tests.
Source: MUHC News Center
Tags: genetics pregnancy gene biotech molar gene+mutations molar+pregnancy nalp7+gene
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Response from:
I.N.
(03/23/10 2:35pm)
The molar pregnancy is an abnormality in the placenta, caused by a problem that occurred during fertilization, at the moment in which sperm penetrates the egg, thus during the conception moment. Molar pregnancies are very rare and appear once in 1000 pregnancies.
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