Low-Cost Genetic Diagnostic Test for Parkinson's Disease

Filed in archive Diagnostics, Methodologies and Instrumentation , Genomics, Proteomics and Bioinformatics on February 23, 2007

Australian researchers have developed a low-cost genetic diagnostic test for Parkinson's Disease (PD). In contrast to the conventional DNA sequencing which costs about $4,000, the new method employs a'gene-sequencing chip' that screens 17 genes in all, including the six known Parkinson's disease genes plus some other suspects in one simple test, at a cost of $500. In addition, the test is simple, and only involves collecting a sample of blood or saliva.

"In addition to providing a genetic diagnosis it is hoped that our chip will eventually be able to pinpoint genetic changes that help to predict a person's prognosis and even the treatment that best suits them.

"As the test is relatively cheap and only involves collecting a sample of blood or saliva, it could also be made available to the patient's relatives and those at risk of developing PD.

"In addition to being a diagnostic tool, this low-cost chip will allow researchers to undertake an Australia-wide gene-mapping study to identify further genes that are involved in PD.

Volunteers are being sought for both the PD GeneChip trial and the Australia-wide PD gene mapping study. See Howard Florey Institute's press release for more information, including the eligibility requirements for participation in the trial.