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Genomics, Proteomics and Bioinformatics
, Microbiology
by ruth on February 18, 2008

Researchers had speculated that blocking pigment formation in staph could restore the immune system's ability to thwart infection. While perusing a magazine on microbial research, Eric Oldfield, Ph.D., of the University of Illinois at Urbana-Champaign read how in 2005 University of California, San Diego researchers knocked out a gene in staph's pigment-making pathway to create colorless-and less pathogenic-bacteria.
Because the approach reduces the virulence of the bacteria by stopping pigment production, it may not cause selective pressures on the population, which can lead to antibiotic resistance. It also targets only S. aureus, possibly reducing side effects.
Source: NIGMS
Tags:
staph+infection
staph+aureus
microbiology
virulence
pigments
pigment+production
genetics
pigment
sta
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/114043
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