biotech
Increasing Yield of Cord Blood-Derived Stem Cells
Filed in archive Stem Cells by ruth on October 19, 2005
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In February this year, researchers from the University of Toronto were able to identify "jelly-like connective tissue surrounding the blood vessels of the human umbilical cord, the so-called "Wharton's Jelly", which is rich in stem cells that may be used to treat leukemia and other blood-cancers, presenting an alternative to bone marrow transplantation. However, not a lot of such mesenchymal cells are found in cord blood. In fact, the amount may not even be enough for use to treat an adult.

In the October issue of Experimental Hematology, researchers from the same university developed a method to identify and remove non-stem cells -differentiated cells, or "lineage-positive" cells- to create a selective environment for stem cells. The researchers also designed a "bioreactor" in which the stem cells grow in a closed and controlled environment. These may pave the production of clinically relevant amounts enough for cell-based therapies. The paper's lead author Peter Zandstra says:

"The hope is that very soon, if the results are the same with the bioreactor as they were with our experiments to date, we will move to clinical trials."


Read more at ScienceDaily.

Permalink: Increasing Yield of Cord Blood-Derived Stem Cells
Tags: cordblood  stemcell  cells  stem  blood  stem+cells  cord+blood  increasing+yield 
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