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Gene Therapy
by ruth on January 27, 2009
Photo courtesy of iStockphoto, Image# 852788A study published in the journal Human Gene Therapy reports of the first clinical evidence that gene therapy reduces symptoms in patients with rheumatoid ar...
Scientists from the University of Michigan will begin a phase 1 clinical trial for the treatment of cancer-related painusing gene therapy: a novel gene transfer vector injected into the skin to delive...
In this month's issue of Plastic and Reconstructive surgery, doctors report of using skin flaps to deliver anti-cancer proteins on rat tumors, resulting in a 79 percent reduction in tumor volume.
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Gene Therapy
by ruth on April 17, 2008
Using gene therapy, researchers have demonstrated in rats that increasing the levels of dopamine D2 receptors in the brain can reduce use of cocaine by 75 percent.
"By increasing dopamine D2 rec...
Researchers have identified the cells responsible for neurofibromatosis type1, a genetic disease characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the s...
Using in-vitro fertilization techniques, scientists have successfully created an embryo with DNA material from three donor parents: nuclear DNA material from the mother and father, and mitochondrial D...
Researchers have identified a gene target called 14-3-3zeta for selective anti-cancer drugs. Using RNAi techniques, they discovered that when 14-3-3zeta is turned off, lung cancer cells become less ab...
By altering a single gene in an animal model, researchers have demonstrated that the effects of the fragile X mutation can be reversed. As such, this research offers potential treatment of fragile x s...
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Gene Therapy
by ruth on November 21, 2007
A gene-transfer technique is undergoing Phase I trials to test its safety in people with a form of hereditary blindness called Leber congenital amaurosis type 2, or LCA2.
The first adult subject rec...
During an international meeting of stem cell scientists in Milan, Italian scientists report on the use of stem cells to replace damaged corneal tissues in the eye and to treat Epidermolysis Bullosa, a...
Using two-dimensional gel electrophoresis and mass spectrometry, 27 differentially expressed protein biomarkers for colorectal adenoma have been identified. The differential expression of two of these...
untreated brain
Photo: Plaques comprised of amyloid-beta are the hallmark pathology of Alzheimer's disease. In this study, the scientists used an amyloid-degrading enzyme to clear these amyloid c...
Results of a clinical trial funded by Bayhill Therapeutics, Inc. shows that BHT-3009, a newly developed DNA vaccine against multiple sclerosis appears safe and may produce beneficial changes in the br...
Researchers have discovered that metformin, a commonly prescribed diabetes drug, slows down the growth of cancer cells lacking p53, a key regulatory gene that regulates Cell division and several metab...
A collaborative group of scientists have determined that mutations in the gene LKB1, which often results to Peutz-Jeghers syndrome, a condition characterized by intestinal growths and an increased ris...
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Gene Therapy
by ruth on June 18, 2007
Researchers may have discovered a way to restore hearing in individuals with a genetic hearing loss resulting form a mutation of a gene known as KCNQ4, which affects the formation of hair-like project...
In a study published in Nature Nanotechnology, researchers have shown that bacteria may be used to deliver "smart nanoparticles" into a cell to precisely position sensors, drugs or DNA for t...
An internation group of scientists have identified the thirteenth gene to be linked to Leber's congenital amaurosis (LCA), an inherited retinal degenerative disease characterized by severe loss of...
Using gene therapy, researchers have successfully blocked the pain response in an animal model of neuropathic pain, a type of chronic pain resulting from damage to nerve fibers due to injuries or dise...
Using gene therapy, scientists have been able to reverse blindness in mice with achromatopsia, a rare hereditary color blindness affecting about 1 in 30, 000 Americans.
Within two months of the gene t...
A team of UCSF scientists has received a $15 million grant from the National Institute of neurological Disorders and Stroke to study the genetics of epilepsy. The project is known as the Epilepsy Phen...
Scientists report of a new prototype drug, designed to treat Duchenne muscular dystrophy but which may be useful in the treatment of up 1800 different genetic diseases. The drug, called PTC124, has re...
A preliminary clinical trial has demonstrated that an intravenuously administered nanoparticle containing the FUS1 gene shows clinical activity in stage 4 Lung Cancer Patients. FUS1 can induce apoptos...
In addition to surgery, radiation and chemotherapy, there may now be an additional treatment modality for cancers: dual gene therapy.
In a preclinical study, two tumor-suppressing genes, packaged in...
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