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Genomics, Proteomics and Bioinformatics
by ruth on February 27, 2008
Hypotrichosis simplex is a group of nonsyndromic human alopecias. We mapped an autosomal recessive form of this disorder to chromosome 13q14.11-13q21.33, and identified homozygous truncating mutations in P2RY5, which encodes an orphan G protein-coupled receptor. Furthermore, we identified oleoyl-L-alpha-lysophosphatidic acid (LPA), a bioactive lipid, as a ligand for P2Y5 in reporter gene and radioligand binding experiments. Homology and studies of signaling transduction pathways suggest that P2Y5 is a member of a subgroup of LPA receptors, which also includes LPA4 and LPA5. Our study is the first to implicate a G protein-coupled receptor as essential for and specific to the maintenance of human hair growth.
The researchers are hopeful that these findings may be useful in discovering new therapeutic approaches to the treatment of hair loss.
Permalink: Gene Plays a Role in Hair Loss Identified
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/115105
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Vote for Gene Plays a Role in Hair Loss Identified:
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Rating: 8.29 out of 7 vote(s) cast.
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Response from:
Peter
(06/17/08 5:07am)
Response from:
rohan
(09/11/08 3:12am)
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I am a 32 years old male of korea and have been worried with my hair loss. I have light skin and dark straight hair but when i listen about the IHT 9 herbal hair regrowth shampoo. and tried. After using it my hair starts growing. herbal hair shampoo is really a surprise gift for me. thanks to IHT 9 herbal hair shampoo.
Response from:
rohan
(09/11/08 3:14am)
Hi
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I am 28 years old i have been shedding hair like crazy over the past two year...... i am not sure why this is happening.i got my blood tests. i just want to know i have started searching in internet for hair regrowth products than i found on the is herbal hair shampoo i have seen many good comments for this product,and when i use the herbal hair shampoo now my hair is very good thanks to herbal hair shampoo..
Response from:
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(09/11/08 4:12am)
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Response from:
herbalhairshampoo
(11/06/09 6:25am)
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here is the website
http://www.herbal-hair-shampoo.com/hair-loss-remedy.html