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Genomics, Proteomics and Bioinformatics
by ruth on April 12, 2007
The gene, called Dmc1, provides the code for a key protein involved in meiosis, the process that produces sperm and egg cells for reproduction. These sex cells contain only one set of chromosomes that combine during conception and create an embryonic cell with two chromosome sets, one from each parent.
The Dmc1 mutation causes a change in an amino acid that blocks meiosis in its tracks, preventing sperm production.
This is the first time that a dominant mutation that leads specifically to infertility in a mammal has been discovered, and may be instrumental in identifying whether such genetic disruptions also cause infertility in male humans.
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/63066
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Vote for Gene Mutation Causing Infertility in Male Mice:
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Rating: 10.00 out of 4 vote(s) cast.
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Response from:
Leslie Feldman
(04/12/07 7:28pm)
Response from:
Mari
(04/23/07 2:29pm)
Hi everyone, I came across a book that might be relevant to the topic discussed here.
It's called "The')" rel="nofollow">http://www.ovarian-cysts-pcos.com/dietbook">"The
Natural Diet Solution
for PCOS and Infertility" by Dr. Nancy Dunne.
It's a comprehensive book that covers dozens of PCOS and dietary topics.
It's called "The')" rel="nofollow">http://www.ovarian-cysts-pcos.com/dietbook">"The
Natural Diet Solution
for PCOS and Infertility" by Dr. Nancy Dunne.
It's a comprehensive book that covers dozens of PCOS and dietary topics.
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Sperm making cells accumulate mutations in DNA. There is a male biological clock and 33-35 and up is advanced paternal age and detrimental to the genetic health of offspring. It is waiting to father that results in autism, schizophrenia, cancers,anti-social personalities, Alzheimer's, diabetes 1, etc. and infertility for the kids.