Gallotannins from Mangoes May Prevent Colon and Breast Cancer
Filed in archive Food and Agriculture on January 11, 2010
© Little Jak-JakPolyphenol extracts from mangoes have been found to have anti-cancer activity, particularly against colon and breast cancer, despite the fruit's comparatively low antioxidant activity.
Mango showed some impact on lung, leukemia and prostate cancers but was most effective on the most common breast and colon cancers.
"What we found is that not all cell lines are sensitive to the same extent to an anticancer agent," she said. "But the breast and colon cancer lines underwent apotosis, or programmed cell death. Additionally, we found that when we tested normal colon cells side by side with the colon cancer cells, that the mango polyphenolics did not harm the normal cells."
The researchers discovered that the bioactive compounds possibly responsible for the anti-cancer effect is a class of polyphenolic compounds called gallotannins. This compound apparently interrupted the cell cycle. Clinical trials are being planned to test mango phenolics on individuals who have increased inflammation in their intestines with a higher risk for cancer.
© Little Jak-Jak
"What we found is that not all cell lines are sensitive to the same extent to an anticancer agent," she said. "But the breast and colon cancer lines underwent apotosis, or programmed cell death. Additionally, we found that when we tested normal colon cells side by side with the colon cancer cells, that the mango polyphenolics did not harm the normal cells."
Tags: functiona+food superfood cancer antioxidants colon colon+breast breast+cancer prevent+colon
Vote for Gallotannins from Mangoes May Prevent Colon and Breast Cancer:
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Rating: 9.50 out of 2 vote(s) cast.
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Response from:
Personal trainers london
(04/20/10 8:00pm)
Nice Post. It's very good to know that extracts of mangoes are used to cure breast cancer. This is one of the most cheapest remedy for curing cancers. Now most of the women can be cured through it.
Response from:
Tom Muller
(09/12/10 3:47am)
Does this mean that women can reduce the risk of getting breast cancer by either having more mangos in their diet or by a type of vitamin of some kind?
Either way this is a great step forward in fighting cancer and that it's had results on other type as well should mean it's a very promising step forward.
Either way this is a great step forward in fighting cancer and that it's had results on other type as well should mean it's a very promising step forward.
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