biotech

Fruitfly Gut Stem Cells Similar to Human's

Filed in archive Stem Cells on December 13, 2005

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In an article published online last week in Nature (abstract only, full-text available upon subscription), scientists from the Carnegie Institution's Department of Embryology have found that not only do adult fruitflies have stem cells lining their gut like humans do, but that
... like vertebrates, the stem cells are multipotent, which means that they can turn into different cell types, and that Notch signaling is as essential in flies in controlling how stem cells transform into different intestinal cells as it is in humans. Notch signaling was also found to instruct stem cells how to differentiate, a role that has as yet to be identified for Notch signaling in vertebrates.


Given this similarity, fruit flies may be instrumental as a model that will help in understanding human digestive disorders, including some cancers, and for developing therapeutics.

Source: Carnegie Insitution News Release

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Tags: stemcells    stem  cells  biotech  stem+cells  fruitfly+stem  similar+human 

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