Fat Hormone Leptin Also Targets Lentromedial Hypothalamus
Filed in archive Drugs, Vaccines and Therapeutics on January 29, 2006

A group of researchers identifies a new region in the brain where the hormone leptin acts upon and subsequently control the regulation of body weight. They report that, in mice, in addition to the area called the arcuate nucleus (ARC) of the hypothalamus, which is already known to be a target of leptin signaling, an area referred to as the ventromedial hypothalamus (VMH) is also important in leptin response.
The researchers noted that the combined effects on obesity of the Deficiency of VMH leptin receptors and high-fat feeding were greater than expected from the individual components added together.
"This synergistic interaction strongly suggests that leptin action on [the VMH neurons] plays a particularly important role in resisting high-fat-diet-induced obesity."
The results of the mice experiments are published in Neuron (January 19, 2006, DOI 10.1016/j.neuron.2005.12.021).
Read more from the Science Daily.

"This synergistic interaction strongly suggests that leptin action on [the VMH neurons] plays a particularly important role in resisting high-fat-diet-induced obesity."
Tags: obesity leptin biotech hormone hypothalamus hormone+leptin lentromedial+hypothalamus also+targets
Vote for Fat Hormone Leptin Also Targets Lentromedial Hypothalamus:
|
Rating: 7.50 out of 2 vote(s) cast.
|
Most Popular
Best of
Biotech Hubs and Facilities
Biotech/Science Blogs
Corporate and Industrial News
Diagnostics, Methodologies and Instrumentation
Did you know
Drugs, Vaccines and Therapeutics
Energy, Environment and Ecology
Food and Agriculture
Gene Therapy
Genomics, Proteomics and Bioinformatics
Information About
Meetings and Other Events
Microbiology
Misc
Nanomedicine
Other Biotechnology News
Patents and Intellectual Property Rights
Quick introduction
Stem Cells
