Antimicrobial Peptides from Amphibian Skin Against HIV Transmission
Filed in archive Drugs, Vaccines and Therapeutics on September 22, 2005
In the September 2005 issue of the Journal of Virology, researchers identified three peptides from amphibian skin-- caerin 1.1, caerin 1.9, and maculatin 1.1-- capable of inhibiting infection within minutes of exposure to the virus.
"These data suggest that amphibian-derived peptides can access DC-sequestered HIV and destroy the virus before it can be transferred to T cells. Thus, amphibian-derived antimicrobial peptides show promise as topical inhibitors of mucosal HIV transmission and provide novel tools to understand the complex biology of HIV capture by DC's."
Read the article's abstract here (subscription needed to read full article).
Tags: antimicrobial HIV biotech amphibian peptides antimicrobial+peptides amphibian+skin skin+against
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