biotech
Antidepressant Drug Mianserin Extends Lifespan of C. elegans
Filed in archive Drugs, Vaccines and Therapeutics by ruth on November 24, 2007
Scientists have discovered that mianserin, an antidepressant drug, can extend the lifespan of of the nematode Caenorhabditis elegans, a commonly used animal model, by about 30 percent.

Antidepressant Drug Mianserin Extends Lifespan of C. elegans


"Our studies indicate that lifespan extension by mianserin involves mechanisms associated with lifespan extension by dietary restriction," said Buck, a member of the Basic Sciences Division of the Fred hutchinson Cancer Research Center in Seattle. "We don't have an explanation for this. All we can say is that if we give the drug to caloric restricted animals, it doesn't increase their lifespan any further. That suggests the same mechanism may be involved."

The study has been published recently in Nature. Read more from HHMI.

Permalink: Antidepressant Drug Mianserin Extends Lifespan of C. elegans
Tags: aging  lifespan  antidepressant  mianserin  drug  antidepressant+drug  lifespan+elegans  extends+lifespan 
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