Anti-Cancer Potentials of Celastrol Plant Derivative
Filed in archive Drugs, Vaccines and Therapeutics on February 15, 2010
Scientists report that Celastrol, anti-inflammatory plant derivative used in Chinese medicine, that may have potentials in cancer treatment. Apparently, Celastrol inactivates heat shock protein 90, a protein crucial to the development of cancer cells.
"The celastrol induces the protein to form fibrils and clusters it together, which inactivates it," said Dr. Chadli, whose research was published in the January edition of The Journal of Biological Chemistry. "When they are clustered, they're not available for other functions that help cancer grow."
Dr. Chadli envisions future studies on cancer patients using even more potent derivatives of celastrol.
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Tags: cancer celastrol biotech more plant plant+derivative cancer+potentials anti+cancer
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