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Drugs, Vaccines and Therapeutics
by ruth on December 29, 2006

JAA-F11, targets a particular disaccharide, an antigen known as TF-Ag, which aids the adhesion and spread of certain cancer cells. While the antibody did not kill the cancer cells, it blocked stages of cancer-cell growth that allow the cells to adhere to organ tissue, the research showed.
Mice with breast-cancer tumors that received the antibody had a median survival time of 72 days, compared to 57 days for the animals that did not receive JAA-F11, the study found. In addition, exposing cultures of tumor cells to the antibody inhibited cell growth by a statistically significant 16 percent.
According to the authors of the study published in the November issue of the journal Neoplasia, JAA-F11 could also increase the efficacy of existing cancer drugs and may be used as a vehicle for drug delivery, since JAA-F11 bind to the tumor cell surface.
[Source: University of Buffalo, Photo: MedLibrary.org]
Tags:
cancer
breast+cancer
antibody
drug+delivery
chemotherapy
biotech
cancer+metastasis
inhibits+breast
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/47274
Mr Wong
Vote for Antibody JAA-F11 Inhibits Breast Cancer Metastasis:
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Rating: 10.00 out of 4 vote(s) cast.
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Response from:
Paul
(12/30/06 8:36pm)
It is not really good news :(
Response from:
ruth
(01/04/07 8:30am)
what do you mean, paul?
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