Filed in archive
Drugs, Vaccines and Therapeutics
by ruth on December 29, 2006
JAA-F11, targets a particular disaccharide, an antigen known as TF-Ag, which aids the adhesion and spread of certain cancer cells. While the antibody did not kill the cancer cells, it blocked stages of cancer-cell growth that allow the cells to adhere to organ tissue, the research showed.
Mice with breast-cancer tumors that received the antibody had a median survival time of 72 days, compared to 57 days for the animals that did not receive JAA-F11, the study found. In addition, exposing cultures of tumor cells to the antibody inhibited cell growth by a statistically significant 16 percent.
According to the authors of the study published in the November issue of the journal Neoplasia, JAA-F11 could also increase the efficacy of existing cancer drugs and may be used as a vehicle for drug delivery, since JAA-F11 bind to the tumor cell surface.
[Source: University of Buffalo, Photo: MedLibrary.org]
Tags:
cancer
breast+cancer
antibody
drug+delivery
chemotherapy
biotech
cancer+metastasis
inhibits+breast
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/47274
Addthis
Ask
Blinklist
del.icio.us
Digg
Fark
Facebook
Google
Lycos
Ma.gnolia
Mr Wong
Netscape
Netvousz
Newsvine
Reddit
StumbleUpon
Slashdot
Tailrank
Technorati
Wink
Yahoo
Vote for Antibody JAA-F11 Inhibits Breast Cancer Metastasis:
|
Rating: 10.00 out of 4 vote(s) cast.
|
Response from:
Paul
(12/30/06 8:36pm)
It is not really good news :(
Response from:
ruth
(01/04/07 8:30am)
what do you mean, paul?
Subscribe
Use the search to look for other interesting posts
| RSS |  See all blog subscribe options |
 What is RSS? | |
| Yahoo! |
|
| Addthis |
|
| Bloglines |
|
| Newsletter | |
| Follow us on Twitter! |
