Response from: The neurophilosopher    (06/16/06 11:16am)

Sonic is also involved in dorso-ventral patterning of the neural tube; its expression is a marker for floor plate cells.

Any therapies for cardiovascular disease could have potentially disastrrous side effects in pregnant women - one effect of Sonic mutations is cyclopia!

Response from: ruth    (06/16/06 4:09pm)

yes, i did mention in the previous entry that the sonic pathway is primarily inolved in early fetal development.

however, i wouldn't worry about cyclopia just yet. most likely, it will result to some sort of gene therapy but this study could still be decades (if at all) away from being an approved therapy.

Response from: oxytocin    (06/17/06 10:04pm)

Nice to see hedghogs getting the attention they deserve

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