Scientists from the University of Michigan will begin a phase 1 clinical trial for the treatment of cancer-related painusing gene therapy: a novel gene transfer vector injected into the skin to...

In this month's issue of Plastic and Reconstructive surgery, doctors report of using skin flaps to deliver anti-cancer proteins on rat tumors, resulting in a 79 percent reduction in tumor volume....

Using gene therapy, researchers have demonstrated in rats that increasing the levels of dopamine D2 receptors in the brain can reduce use of cocaine by 75 percent. "By increasing dopamine D2...

Researchers have identified the cells responsible for neurofibromatosis type1, a genetic disease characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the...

Using in-vitro fertilization techniques, scientists have successfully created an embryo with DNA material from three donor parents: nuclear DNA material from the mother and father, and mitochondrial...

Researchers have identified a gene target called 14-3-3zeta for selective anti-cancer drugs. Using RNAi techniques, they discovered that when 14-3-3zeta is turned off, lung cancer cells become less...

By altering a single gene in an animal model, researchers have demonstrated that the effects of the fragile X mutation can be reversed. As such, this research offers potential treatment of fragile x...

A gene-transfer technique is undergoing Phase I trials to test its safety in people with a form of hereditary blindness called Leber congenital amaurosis type 2, or LCA2. The first adult subject...

During an international meeting of stem cell scientists in Milan, Italian scientists report on the use of stem cells to replace damaged corneal tissues in the eye and to treat Epidermolysis Bullosa, a...

Using two-dimensional gel electrophoresis and mass spectrometry, 27 differentially expressed protein biomarkers for colorectal adenoma have been identified. The differential expression of two of these...

untreated brain Photo: Plaques comprised of amyloid-beta are the hallmark pathology of Alzheimer's disease. In this study, the scientists used an amyloid-degrading enzyme to clear these amyloid...

Results of a clinical trial funded by Bayhill Therapeutics, Inc. shows that BHT-3009, a newly developed DNA vaccine against multiple sclerosis appears safe and may produce beneficial changes in the...

Researchers have discovered that metformin, a commonly prescribed diabetes drug, slows down the growth of cancer cells lacking p53, a key regulatory gene that regulates Cell division and several...

A collaborative group of scientists have determined that mutations in the gene LKB1, which often results to Peutz-Jeghers syndrome, a condition characterized by intestinal growths and an increased...

Researchers may have discovered a way to restore hearing in individuals with a genetic hearing loss resulting form a mutation of a gene known as KCNQ4, which affects the formation of hair-like...

In a study published in Nature Nanotechnology, researchers have shown that bacteria may be used to deliver "smart nanoparticles" into a cell to precisely position sensors, drugs or DNA for...

An internation group of scientists have identified the thirteenth gene to be linked to Leber's congenital amaurosis (LCA), an inherited retinal degenerative disease characterized by severe loss...

Using gene therapy, researchers have successfully blocked the pain response in an animal model of neuropathic pain, a type of chronic pain resulting from damage to nerve fibers due to injuries or...

Using gene therapy, scientists have been able to reverse blindness in mice with achromatopsia, a rare hereditary color blindness affecting about 1 in 30, 000 Americans. Within two months of the gene...